Focus on olive oil and protein
If youre curious whether a GLP-1 medication might be appropriate for your situation, the most productive first step is a conversation with your endocrinologist particularly one familiar with off-label use and experienced in adjusting insulin regimens in response
Subjective but important
NEJM Dec 2025) 12 None (no approved label) MTC thyroid C-cell (rodent, human relevance unestablished) 28 None published None published Once weekly, subcutaneous Once weekly, subcutaneous US: late 2027 earliest (NDA Q4 2026 at soonest) 22 Already approved (US: 2022/2023/2024
For example, if your compounded semaglutide is 5mg per milliliter and you need 0.25mg, you need 0.05ml, which is 5 units on a standard U-100 insulin syringe
Mechanism of Action Acetyl Group Protection : The attached acetyl group acts as a molecular shield, preventing digestive enzymes from breaking down glutathione prematurely in the stomach and intestines, which allows the intact molecule to reach target tissues like the liver, lungs, and brain
