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Oral citicoline (1,600 mg/day) was given for 60 days followed by 60 days of washout, and the therapeutic cycle was repeated once

doi:10.1002/biot.201400809 Pei J, Huang L (2012) Yeast strain for producing astaxanthin and glutathione by fermentation method and production process thereof

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The hazard ratio was 7.64 (95% CI, 2.21-26.36

All study subjects were randomly assigned to receive treatment with modafinil in a film-coated tablet, 200-300 mg/day, depending on weight (200 mg/day for 30 kg) (group 1) or placebo (group 2) for a 6-week double-blind, randomized clinical trial