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In rats undergoing Roux-en-Y gastric bypass (RYGB), transcript levels of Tlr4, Myd88, Cd14, and downstream pro-inflammatory cytokines including Il1b, Il6, Il18, and Tnfa were significantly reduced in the hypothalamus, suggesting a procedure-specific attenuation of TLR4 signaling
The heterogeneous assortment of secreted vesicles produced by virtually any cell type through diverse biogenesis processes
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