However in contrast to popular belief high dose oral b12 can maintain b12 levels in AIAG or PA as 1% of B12 is absorbed independently of intrinsic factor
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& Gandhi, V
just don't have them right alongside your dose
Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Contact your GP or diabetes care team if you experience: New or worsening swelling that persists for more than a few days or progressively increases in severity Unilateral swelling (affecting only one leg or arm), particularly if painful, which may suggest deep vein thrombosis and requires same-day assessment via your local DVT pathway [17] Swelling accompanied by pain, redness, warmth, or tenderness , which could indicate cellulitis or thrombophlebitis Facial swelling, particularly around the eyes, lips, or tongue , which may represent an allergic reaction or angioedema [18] Rapid weight gain (more than 23 kg in a few days) alongside swelling, which could suggest fluid retention related to cardiac or renal issues [19] Seek urgent medical attention (call 999 or attend A&E) if swelling is associated with: Difficulty breathing or shortness of breath , which may indicate pulmonary oedema or a serious allergic reaction Chest pain or palpitations , potentially suggesting cardiac complications Severe abdominal pain , particularly if accompanied by nausea and vomiting, as this could indicate pancreatitis (a rare but serious adverse effect of GLP-1 receptor agonists)
