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Besides improving glucose control, reducing body weight, and lowering arterial blood pressure (surrogate endpoints), the breakthroughs were the demonstration of a significant reduction in cardiovascular and renal events in patients with type 2 diabetes at high risk

Linearity and Range To establish the solutions of D-Carnitine at varying concentrations ranging from LOQ to 160% of the specification levels (0.05% of D-Carnitine with respect to sample concentration) were prepared and injected into the HPLC system ( Figure 4 )

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