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Headaches may result from dehydration due to reduced fluid intake or gastrointestinal side effects, changes in eating patterns including meal skipping or caffeine withdrawal, blood glucose fluctuations, or individual susceptibility factors

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This indicates that such side effects are uncommon but not negligible. Underreporting : The FAERS database relies on voluntary reporting, which means the actual incidence of these side effects could be higher due to underreporting. Comparative Risk : When compared to the general population or patients using other medications, the incidence of ear-related issues in GLP-1 RA users appears low