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Whether reducing NNMT activity would directly reverse these changes in humans remains an open research question

The Food and Drug Administration approved Zepbound for use by adults with a body mass index, or BMI, of at least 30 or a BMI of 27 or more if a patient also has another weight-related condition, such as high blood pressure, heart disease or obstructive sleep apnea

Rapid in vivo reactivation of herpes simplex virus in latently infected murine ganglionic neurons after transient hyperthermia

2012 (PMID 22129598), which introduced the HGF-dimerization framing, was retracted in 2025 (retraction notice PMID 40312092)

Cancer Med 9(10):34893499 Majewska E, Mrquez J, Albrecht J, Szeliga M (2019) Transfection with GLS2 glutaminase (GAB) sensitizes human glioblastoma cell lines to oxidative stress by a common mechanism involving suppression of the PI3K/AKT pathway

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