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The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

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Glutathione affinity purification is commonly used to isolate and purify glutathione S-transferase (GST)-tagged fusion proteins from total cellular proteins in lysates

Of importance, JM has an eGFR of 50 mL/min/1.73 m 2 with evidence of microalbuminuria

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