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(2020b) identified eEANs in contact with intestinal epithelial cells can detect microbes and their metabolites, specifically SCFAs, bile acids, and neuropeptides, via vagal afferents and subsequently sympathetically modulate gut activity via a CNS-directed circuit (Muller et al., 2020b)

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It protects cells from oxidative damage and helps maintain redox homeostasis, for example by removing peroxides, through its reactive sulfhydryl group (-SH) 13

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