Frequent consumption of high-sugar foods can make it harder for semaglutide to regulate blood sugar effectively
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NICE technology appraisal TA875 (2023) recommends semaglutide 2.4 mg (Wegovy) as an adjunct to a reduced-calorie diet and increased physical activity for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when initiated within specialist weight management services
They might mediate a nausealinked reduction in food intake but might not be involved in mediating the sensation of feeling sick
However, some people find that doing so can cause stinging at the injection site