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The lyophilised cake should dissolve gradually without visible agitation

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Conversely, circadian disruption, chronic overnutrition or long-term high-fat feeding commonly reduce Faecalibacterium abundance and deplete butyrate, changes that are linked experimentally to impaired gut barrier integrity, shifts in mucosal immune tone, increased translocation of microbial products (e.g., LPS) and worsened hepatic inflammation and fibrogenesis (86)

But to maintain that effect, an IV drip had to run constantly, given the peptides rapid clearance