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Notably, FADS1 is expressed at higher levels in LAR and basal-like immunosuppressed (BLIS) subtypes when compared to mesenchymal (MES) and immunomodulatory (IM), whereas FADS2 is present at the highest levels in LAR subtype when compared to all the other TNBC subtypes, thus confirming that the LAR subtype is characterized by overall higher FADS expression levels (Fig

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This means that the drug targets not one, but two unique incretin hormones produced by the human bodywhich has been shown to increase the efficacy of the drug compared to medications that target only GLP-1