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However, the enzyme can, under certain conditions, also inactivate cortisol and corticosterone by catalyzing the oxidation reactions converting cortisol to cortisone and corticosterone to 11-dehydrocorticosterone

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Diltiazem (Cardizem, Others) Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia

Please note that results may vary from person to person and it is always recommended to do a skin sensitivity test before using any new product on your skin