2019;158 doi: 10.1016/j.neuropharm.2019.107748
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
Unlike PDE5 inhibitors and other compounds that act peripherally through vascular mechanisms, PT-141's studied activity originates at the level of the CNS
Research demonstrating collagen stimulation, antioxidant activity, and gene expression changes relevant to skin health applies to male subjects as well as female subjects
Asking if 1mg is 'enough' is like asking if the first gear in a car is 'enough' to win a race
In addition, these medications improve glycemic control, reduce systemic inflammation markers, and may positively influence cardiovascular risk factors