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For functional medicine practitioners, biohackers, and researchers, DSIP represents an exciting tool in the expanding toolkit for restoring sleep, rebuilding resilience, and enhancing healthspan
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Across large RCTs and meta-analyses, these medications consistently reduce hospitalization for HF across the ejection fraction spectrum, with reductions in cardiovascular death and all-cause mortality most firmly established in HFrEF (and in chronic kidney disease and atherosclerotic disease) [6, 14, 41, 42]
