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243 D34-919 blocked the interaction between ALDH1A3 and PKM2 in GBM cells, thereby suppressing the downstream lactylation of XRCC1, which restored the sensitivity of GBM to TMZ-based chemotherapy and radiotherapy in GBM organoid models

Additionally, the growing popularity of GLP-1 receptor agonists as treatments for obesity presents immense opportunities for biosimilar players

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Long-term treatment with liraglutide significantly reduces tau pathology and improves motor function in a transgenic mouse model of tauopathy

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