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Additional potential relevant articles were further retrieved through a manual search of references from original reports
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Although the objective remission rate was low, some patients achieved durable disease control or partial remission
308 Experimentally-induced depletion or attenuation of reactive astroglia markedly exacerbates the clinical progression, spread of inflammation and tissue loss in EAE during the induction phases of the disorder, 81,309,310 whereas similarly induced depletion of proliferating reactive astrocytes at later times during the progressive phase ameliorates disease, and this amelioration is at least in part due to removal of astrocyte Ccl2 production
Chiu CJ, Robman L, McCarty CA, et al