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Specifically, the CD68-positive area in the aortic root sections of the P-Mn/TI@mHSA group was ~11.59%, which was markedly lower than that observed in the PBS control group (39.44%), as well as the Mn/TI@mHSA (30.95%), P-Mn@mHSA (23.39%), and P-Mn/TI@mHSA-N groups (19.70%) (Fig

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Because of rare thyroid tumours seen in animal studies, these drugs are avoided in people with a history of medullary thyroid carcinoma or MEN2