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9 GHK-Cus gene-expression breadth means its effects likely intersect this pathway, and secondary sources routinely claim direct activation

While originally classified as an opioid receptor subtype, sigma-1 receptors are chaperonins located on the endoplasmic reticulum and expressed mainly in the central nervous system in neurons and glial cells in the brain [130, 131]

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10.2174/13816128130105 27 DjakovicZ.DjakovicI.CesarecV.MadzaracG.BecejacT.ZukanovicG.et al (2016)

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