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The beneficial role of tirzepatide on triglyceride levels could be at least partially explained by GIP-induced increased vascularization and lipid uptake in the adipose tissue [81]

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This section reviews alterations in muscle mass, muscle quality, and their underlying mechanisms during GLP-1 RA therapy, as illustrated in Fig

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Recent studies have revealed that mitochondrial activity not only influences cellular energy metabolism but also affects epigenetic modifications, such as histone methylation and acetylation, which are crucial in the regulation of immune responses under hypoxic conditions