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Jaime Almandoz, an endocrinologist and associate professor of internal medicine at UT Southwestern Medical Center

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These color changes indicate oxidative degradation or other chemical reactions that have produced chromophoric (light-absorbing) degradation products

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These findings are consistent with our previous findings [9] but do not fit with the conventional model, whereby GLP-1 secreted into the circulation from the gut mediates the effects of DPP-4 inhibitor action [13]