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Electrophysiological and c-Fos mapping studies in rodent models have demonstrated that amylin receptor activation in these regions inhibits gastric emptying, reduces meal size, and activates downstream satiety circuits projecting to the hypothalamic arcuate nucleus (Lutz et al., Physiology & Behavior, 2010)

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J Hothersall J.S., Gordge, M., Noronha-Dutra, A.A., Inhibition of NADPH supply by 6-aminonicotinamide: eect on glutathione, nitric oxide and superoxide in J774 cells