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In addition, nuclear pores do not restrict diffusion of low molecular weight solutes like GSH [14], which could possibly difficult the establishment of a specific pool of GSH within the nucleus

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Jung Jang E, Kil YS, Ryeon Park H, Oh S, Kyeong Kim H, Gyeong Jeong M, Kyoung Seo E, Sook Hwang E (2014) Suppression of IL-2 production and proliferation of CD4(+) T cells by tuberostemonine O

Both are about eight to ten times too large