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A 2023 analysis of weight loss clinic outcomes showed men on concurrent testosterone replacement and semaglutide achieved 12-15% body weight reduction over 6 months, compared to 8-10% with semaglutide alone in eugonadal males

Retatrutide microdosing means splitting the once-weekly dose into smaller injections taken two to seven times a week

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The standard dosing is provided below: : Start with 2.5mg once weekly for 4 weeks, then increase to 5mg

Diabetologia 53 , 153159 (2010)