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Current therapies (laxatives, antispasmodics, microbiota modulators) are limited by side effects and inconsistent efficacy, underscoring the necessity for tailored, patient-centered care

Employers should keep in mind that indication-based coverage decisions (such as covering GLP-1 drugs for diabetes treatment but not for treatment of obesity or other conditions, such as addiction) can potentially raise concerns under the Americans with Disabilities Act (ADA), the ACA, HIPAAs nondiscrimination requirements, or the Mental Health Parity and Addiction Equity Act, among other laws

Zepbound carries a list price, or the cost to wholesalers, of about $1,080 a month, according to its manufacturer, Eli Lilly and Company

Even after patent expiration, generic entry typically takes 13 additional years for FDA approval and manufacturing scale-up

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