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STEP 1, SURMOUNT-1, and the Jastreboff Phase 2 enrolled different populations

Both of these effects can impair vitamin B12 absorption

Keep a daily log that includes: Injection date, time, dose, and site Appetite level on a 1 to 10 scale Energy level on a 1 to 10 scale GI symptoms (nausea, bloating, constipation, diarrhea) with severity rating Weight (same time each morning, same conditions) Notable observations (food cravings, mood changes, sleep quality) After two to four weeks at each dose level, review your log for patterns

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Combined with Mounjaros effect of slowing stomach emptying, this can temporarily change how food moves through your digestive system

The oral formulation offers convenience, but injectable forms may provide faster results