Pay in 4 interest-free payments of $6.39 Learn more
Ships within 48 hours · Estimated delivery Sep 4 - Sep 9
Tirzepatide is a dual GIP 1 and GLP-1 receptor agonist commonly used in medically supervised weight-loss programs
These cases demonstrate the utility of GLP-1 agonists in treating dermatologic conditions that are refractory to other therapies and further highlight the potential of GLP-1 agonists in treating skin disease
Another possible reason is inflammation shifts
Patients should be counseled that GLP-1 medications are most effective as part of comprehensive lifestyle modification, not as a substitute for healthy eating patterns
It has been 35 years since GLP-1 was discovered, and it is no longer a new target, but its long-acting effect is far from over
While hyperinflammation due to proinflammatory cytokine overproduction has been frequently documented, it is recently recognized that the immune response is markedly suppressed in some cases by the expansion and activity of MDSCs (myeloid-derived suppressor cells) and FoxP3 + Tregs (regulatory T cells)
