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Moro F, Gorgone G, Li Volti S et

Such assumptions introduce potential bias, compromise data interpretation, and ultimately reduce the overall validity of the findings [60,69,137,138,139]

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Moreover, in attempts to replace the hydroxyl group of the tyrosine moiety to avoid potential problems with phase II metabolism compound 27 was prepared ( 27 ) is 10-fold less potent than 25 demonstrating that interactions with the hydroxyl group is important, although not critical for activity

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Locci-Molina N, Wang A, Kroumpouzos G

Figure 7: Changes in the levels of A) IL-1-beta, B) TNF-alpha, and C) IL-10 in each of the four different experimental groups included in the first part of the study