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specifically examined patients with MASLD cirrhosis and type 2 diabetes, finding that GLP-1 receptor agonist initiation was linked to reduced risk of unfavorable liver outcomes including hepatic decompensation events and mortality from any cause (aHR: 0.78, 95%CI: 0.68-0.90) relative to non-users, suggesting potential benefits even in advanced liver disease populations [58]

[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Kumar A., Sehgal N., Kumar P., Padi S.S.V., Naidu P.S

doi: 10.1016/j.bone.2009.01.373 21

Enhanced permeability of the BBB and subsequent leakage of blood contents exacerbate BBB disruption, fueling a vicious cycle detrimental to the imbalance of the CNS, ultimately contributing to neuronal degeneration, and driving neurodegenerative disorders pathophysiology

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