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Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

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Dixon's group demonstrated that the GSH exporter MRP1 sensitizes HPA1 erastin-treated cells to ferroptosis and concordantly, MRP1 inhibition leads to a retention of GSH and leads to ferroptosis resistance (58)

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YFP fluorescence was collected using the 488 nm laser and the 530/30 bandpass filter, and ITGA6-647 fluorescence was collected using the 640 nm laser and the 670/14 bandpass filter

Journal of molecular endocrinology 53 , 105115, doi:10.1530/JME-13-0200 (2014)