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doi: 10.2217/bmm-2020-0308 7 QiXMWangJXuXXLiYYWuYG

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According to The Canadian Dermatology Association, approximately 1 million Canadians are currently living with the condition

According to overall findings, OLE inhibits activation of the RAGE/HMGB1 pathway and NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome and NF-B pathway, thus reducing neuroinflammation

Treatment significantly decreased tracheal hyperreaction (dyspnea), and reduced serum total IgE and the IgG1/IgG 2A/2B ratio in a dose-dependent manner (0.2 g/kg, 0.5 g/kg) [165]

After 72 hours of incubation, cells were counted and 50,000 cells per each condition were taken for the luminescent assays