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For example, a sheep model of gestational diabetes demonstrated reduced surfactant protein production and expression of GR/11-HSD1 in the fetal lung (295)

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Follow-up studies combining mitochondrial metabolite profiling, organelle transport assay and structure-guided mutagenesis identified a critical role of SLC25A39 in mitochondrial glutathione uptake, a discovery that has also been independently reached by a recent report 14