Phosphodiesterase-5 inhibitors remain appropriate adjuncts
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His past medical history included morbid obesity, diabetes on 1 oral agent with no known target organ disease, nonischemic cardiomyopathy diagnosed 6 years ago (with the last recorded left ventricular ejection fraction of 40% on transthoracic echocardiogram), and nonsignificant smoking history
Baseline kidney function assessment is essential before starting semaglutide, particularly for patients on anticoagulation
Novo is trying to keep ahead of rival Eli Lilly, whose Mounjaro diabetes product is also expected to gain approval as a weight-loss drug.
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