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doi: 10.1016/j.neurol.2014.03.005 163 BuskiewiczIAMontgomeryTYasewiczECHuberSAMurphyMPHartleyRCet al

As the name suggests, this is a form of cell death caused by copper, in which copper ions directly bind to protein lipoylation components in the tricarboxylic acid circulation pathway, causing abnormal aggregation of lipoylated proteins and loss of iron-sulfur cluster protein, resulting in protein toxic stress responses and cell death (172)

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t = 0.39, p = 0.7)

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