Gastrointestinal effects such as nausea and diarrhea that are caused by the medication will stop once the medication is stopped
The researchers looked at data from 4,286 people out of a total of 17,605 from the landmark Semaglutide and Cardiovascular Outcomes (SELECT) trial who were randomly assigned either semaglutide or a placebo who were followed up over an average of more than three years
References For Further Reading (1) M V Graf and A J Kastin (1984) Delta-sleep-inducing peptide (DSIP): a review Neuroscience Biobehavioural Reviews, 1984 Spring, Volume 8 (Issue 1), Pages 83-93
However, hurdles to their widespread use, such as manufacturing cost, delivery system, and side effects remain, especially in low- and middle-income countries
The GLP-1 medication landscape has shifted dramatically in 2026, with self-pay options now competing directly with insurance-dependent pathways
Most patients begin noticing weight loss within the first few weeks of treatment