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Molecules 15:432441 Chang KT, Lii CK, Tsai CW, Yang AJ, Chen HW (2008) Modulation of the expression of the class of glutathione S-tranferase by Adrographis paniculata extracts and adrographolide

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Patients should not use glutathione as a primary treatment, but it may be effective in conjunction with other psoriasis treatment methods

NRF2 regulates heme degradation, thus removing excess amounts of the prooxidant molecule heme from the cellular pool

The governance of stem cell function by an NRF2-sirtuin axis is further supported by evidence that SIRT6 knockout MSCs exhibited a functional decay driven by redox abnormalities and increased sensitivity to oxidative stress (Pan et al., 2016)