But these methods dont work for everyone, particularly those struggling with high-frequency or chronic migraines
In randomized controlled trials, semaglutide has produced average weight loss of approximately 15% of baseline body weight, while tirzepatide has delivered reductions exceeding 20% in some study populations
Dysesthesia A skin sensitivity or burning sensation has been flagged as a signal to monitor in Phase 3
But what I'm most passionate about is this: let the medication be a bridge, not the finish line
Some researchers move from retatrutide to semaglutide or tirzepatide for maintenance, particularly if cost or availability changes
Still, more transparency is better than less, and were seeing Trump roll out some initiatives we expected (Medicaid cuts, MAHA movement, more price transparency)