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Parkinsons Disease (PD) Neuronal loss in the substantia nigra (SN) is a neuropathological characteristic of PD, which leads to striatal dopaminergic insufciency and an increase in the synthesis of -synuclein in neuronal inclusions [ 176 ]

The resulting ranked paths highlight likely molecular routes connecting sources to the target within the network

This approach costs less overall and allows more precise management of each component

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