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The paucity of data regarding their safety during pregnancy and lactation causes a dilemma for the physician

MRI may show cerebral white matter atrophy, ventricular enlargement, periventricular gliosis, optic nerve atrophy, delayed myelin formation or dysplasia, cerebellar hypoplasia, cerebellar hemisphere atrophy, and hypersignal in the subcortical white matter [116, 117]

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[55] Adipose tissue and metabolism [edit] In obesity, adipose tissue often becomes dysfunctional