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In SURMOUNT-1 (N=2,539), tirzepatide 15 mg produced nausea in 39% of participants

GLP-1 agonists are candidate adjuncts against the weight gain that undermines quitting (Herman & Schmidt, 2024)

Doses adjustments are considered every 4 weeks as needed

Even though there is no evidence of interactions between semaglutide and cannabis nor of reports of reduced efficacy, this is an area that requires monitoring

Weight loss without muscle strategy is a short-term win and a long-term problem

In addition, the semaglutide injection (Ozempic) reduces the risk of stroke, heart attack, and death in adults with type 2 diabetes and heart disease