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Following repeated oral exposure for 4 weeks (1.75, 7, 28 mg/kg/day), granulomatous inflammation was observed, characterised by infiltration of macrophages and occasional lymphocytes into terminal bronchioles and alveolar spaces

Study Identification and Selection Approach The initial search yielded a large body of literature across peptide agents and clinical domains

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The structures were deposited in the Protein Data Bank under accession codes 28MT (truncated model, C20 persulfidated), 28MU (truncated model, C20 sulfonated), 28MV (full length model, as isolated), 28MW (full length, C201S variant), 28MX (full length, C408S variant), and 28MY (full length, C201S/C408S variant)