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References Blanpain C, Fuchs E

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To date, pathological studies in MS have not detected any differences in the number of OPCs or mOL in male and female MS brain specimens (48)

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For instance, while quercetin has been reported to activate both enzymes, curcumin has shown potential as an activator of SIRT1, promoting its deacetylase activity and contributing to anti-inflammatory effects 178

It modulates the GABAergic system by increasing GABA binding to its receptors, producing an anxiolytic effect without the sedative effects or addictive potential of benzodiazepines