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They not only directly activate the expression of GAD65/67 and VGAT, ensuring the GABAergic properties of interneurons, but also regulate genes such as Arx, guiding interneurons to migrate from the ventral forebrain to the cortex and form inhibitory circuits

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This leads to a lot of wasted money and lower efficacy of treatment

In 2008, this report was published: Title: Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinsons disease