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Continued Treatment With Tirzepatide for Maintenance of Weight Reduction: The SURMOUNT-4 Randomized Clinical Trial

A fresh pharmacological approach resets some of the adaptive mechanisms that cause plateaus

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Against Naltrexone/Bupropion, observed associations with reduced incidence emerged for cataracts (HR 0.37, 95% CI: 0.180.75, p = 0.004), oculomotor binocular dysfunction (HR 0.46, 95% CI: 0.270.79, p = 0.004), dry eye disease (HR 0.36, 95% CI: 0.180.73, p = 0.003), and ametropic accommodative dysfunction (HR 0.50, 95% CI: 0.290.87, p = 0.012)