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To determine a MIPS payment adjustment factor for each MIPS eligible clinician for a MIPS performance period, CMS compares the MIPS eligible clinician's final score for the given year to the performance threshold CMS established for that same year in accordance with Section 1848(q)(6)(D) of the Act

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In malignant peripheral nerve sheath tumors, these inactivations of PRC2 components significantly co-occurred with somatic alterations of CDKN2A (81% of all MPNST) and NF1 (72% of non-NF1-associated MPNST)

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