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Thus, ferroptosis directly impairs macrophages through the release of DAMPs

The aforementioned findings suggested that SLC7A11 and HMOX1 may exert their effects by modulating the quantity of relevant innate or adaptive immune cells, as well as their recruitment and immune functions

Liver and WAT transcriptomic analyses To examine downstream systemic effects of genetic and pharmacologic manipulations, transcriptomic analysis was conducted on inguinal WAT (Fig

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Additional samples were preserved in 10% formalin for histological examination

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