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The sustained generation of 1 O 2 by ZFO, ZFP, and ZFP + H 2 O 2 under US irradiation was demonstrated in Figs

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Enrolled patients were randomized in a 5:1 ratio to receive either tirzepatide or matched placebo by once-weekly (QW) subcutaneous (SC) injection in one of two cohorts: in Cohort 1 (2.510.0 mg), patients assigned to tirzepatide received 2.5 mg for the first 4 weeks, with the dose increasing by a further 2.5 mg every 4 weeks, to the maximum dose of 10.0 mg