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Elevated free fatty acid levels have been linked to impaired insulin signaling 159 , and serum fatty acids that enter the liver can be incorporated into TGs, contributing to steatosis and insulin resistance 69,160,161

The precise relationship of the neuroimaging findings to the ocular features of SANS has not been established

TRANSCEND-T2D-1, the companion type 2 diabetes trial, was published simultaneously in The Lancet and showed A1C reductions of up to 2.0% and weight loss of up to 36.6 lbs, while TRIUMPH-1 supplied the knee osteoarthritis and obstructive sleep apnea data

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