how does glp-1 work for insulin resistance GLP-1R and Diabetes GLP-1 RA education

According to the 2023 ADA standards of care in diabetes (12), GLP-1 RAs with demonstrated CV benefit are considered for T2DM patients with established ASCVD or at high risk for ASCVD to reduce the risk of MACE

These improvements occurred even with modest weight loss suggesting the possibility that GLP-1s have direct anti-inflammatory effects in the airways

The 15 mg dose of tirzepatide produced a mean percent change in weight of almost 21% by week 72, which, when youre talking about a mean baseline body weight of 105.6 kg in that group, is a LOT of kgs dropped

Both drugs are also legally compounded (ie, made to order) by Australian pharmacies to meet demand amid a global shortage a practice the TGA is trying to ban due to the lack of safety testing

GLP-1R agonists: recent advances, current gaps, and future challenges

During clinical trials for those conditions, researchers noticed an interesting side effect: patients kept losing weight