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Next, we measured the production of the reduced form of nicotinamide adenine dinucleotide (NADH) as a readout of Ldh activity in control and Ldh knockdown hemocytes

Pathway analysis demonstrated that these metabolites were enriched with metabolites from SAA metabolic pathways, particularly cysteine and methionine metabolism (Fig

A recent report showed that basal GSH levels are significantly elevated in MM patients after receiving therapy, which is consistent with our observation of resistant MM cell lines increasing GSH after L-PAM treatment

Total program: 12 weeks

In addition, studies suggest roles in angiogenesis, peripheral nerve outgrowth, antioxidant defense, and modulation of inflammatory activity, including in models of chronic pulmonary injury[2]